The 2021 TransPride Pittsburgh Health and Wellness Conference perseveres during a time when transgender and gender diverse individuals, particularly young people, are the targets of a coordinated legislative campaign that seeks to revoke their rights to participate in sports as their affirmed gender while also criminalizing and denying critical access to gender-affirming care. This conference rallies against these issues by centering the lives and lived experiences of the transgender and gender non-conforming community. We are striving to bring together not only community members but their families, allies, and healthcare professionals in a space of mutual learning through shared perspectives and experience.