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Pharmacogenomics in Practice: Primary Care (2025)
Pharmacogenomic (PGx) implementation is increasing in the US, especially in primary care where there is wide variability in medication response and strong evidence of the impact of genetic variation on medication outcomes. Commonly prescribed medications have Clinical Pharmacogenetics Implementation Consortium (CPIC) and/or FDA have PGx-based prescribing guidance. However, primary care clinicians report low knowledge and confidence in using PGx information for adjusting dose or drug selection. This barrier must be overcome by clinicians who are responsible for integrating PGx into their practice to achieve positive outcomes.
Pharmacogenomics in Practice: Primary Care
A 2-hour, self-paced, online training for clinicians seeking to integration pharmacogenomics (PGx) in their primary care practice.
Integrating PGx into your mental health practice
- Introduction – Presented by: Philip Empey, PharmD, PhD
- Statins - Presented by: James Coons, PharmD
- Beta blockers - Presented by: James Coons, PharmD
- Pain - Presented by: D. Max Smith, PharmD, BCPS
- Mental health - Presented by: James Stevenson, PharmD, MS
- Antiseizure medications – Presented by: Philip Empey, PharmD, PhD
- Proton pump inhibitors – Presented by: Philip Empey, PharmD, PhD
- Conclusion – Presented by: Philip Empey, PharmD, PhD
Target Audience
All healthcare professionals, including: Nurses, Nurse Practitioners, Pharmacists, Physicians and Physician Assistants.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Identify gene-drug pairs with high level PGx evidence.
- Describe how PGx variation affects pharmacokinetics and pharmacodynamics.
- Recognize the availability of evidence-based PGx guidelines.
- Review key clinical trials evaluating the integration of PGx in primary care.
- Give examples of clinical situations when PGx is likely to be useful.
- Identify specific challenges in PGx implementation.
Disclaimer Statement:
The information presented at this activity represents the views and opinions of the individual presenters, and does not constitute the opinion or endorsement of, or promotion by, the UPMC Center for Continuing Education in the Health Sciences, UPMC / University of Pittsburgh Medical Center or Affiliates and University of Pittsburgh School of Medicine. Reasonable efforts have been taken intending for educational subject matter to be presented in a balanced, unbiased fashion and in compliance with regulatory requirements. However, each program attendee must always use his/her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.
Faculty:
Planning Committee:
- James Coons, PharmD (University of Pittsburgh School of Pharmacy, Pittsburgh, PA)
- Jill Bates, PharmD, MS (University of North Carolina Medical Center, UNC Eshelman School of Pharmacy, Chapel Hill, NC)
- Lucas Berenbrok, PharmD, MS (University of Pittsburgh School of Pharmacy, Pittsburgh, PA)
- Deepak Voora, MD (Duke University School of Medicine, Department of Medicine, Durham, NC)
- Trina Walker, DNP, APRN, FNP-C (Creighton University, Ohmaha, NE)
- Nguyen Park, MS, PA-C, DFAAPA, (Wayne State University, Detroit, MI)
- D. Max Smith, PharmD, BCPS (Clinical PGx Specialist at MedStar Health & Asst. Professor at Georgetown University Medical Center, Washington, DC)
Course Director:
Philip Empey, PharmD, PhD, FCCP (University of Pittsburgh School of Pharmacy, Pittsburgh, PA)
Presenters:
- Introduction – Philip Empey, PharmD, PhD
- Statins - James Coons, PharmD
- Beta blockers - James Coons, PharmD
- Pain - D. Max Smith, PharmD, BCPS
- Mental Health - James Stevenson, PharmD, MS
- Antiseizure medications – Philip Empey, PharmD, PhD
- Proton pump inhibitors – Philip Empey, PharmD, PhD
- Conclusion – Philip Empey, PharmD, PhD
Conflict of Interest Disclosure:
Dr. Coons discloses that he receives grant/research support from Heart Rhythm Society, and Bristol Myers Squibb. He is a consultant for Merck, Bristol Myers Squibb, AstraZeneca and Johnson & Johnson.
No other planners, members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.
In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physician (CME)
The University of Pittsburgh designates this enduring material activity for a maximum of 2.0 AMA PRA Category 1 Credit[s]™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Nursing (CNE)
The maximum number of hours awarded for this Continuing Nursing Education activity is 2.0 contact hours.
Physician Assistant (AAPA)
The University of Pittsburgh has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 2.0 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.
Pharmacy (CPE)
This knowledge-based activity provides 2.0 contact hours of continuing pharmacy education credit.
Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.
Available Credit
- 2.00 AAPA Category I CME
- 2.00 ACPE PharmacyThe UPMC Center for Continuing Education in the Health Sciences is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a Provider of continuing pharmacy education.
- 2.00 AMA PRA Category 1 Credit™The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
- 2.00 ANCCUPMC Provider Unit is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation
- 2.00 Attendance
PLEASE NOTE: Your NABP and DOB must be in your profile in order to have credits submitted to the ACPE and pharmacy credits awarded.
The content for this training is not hosted on this website, please access the training via the Test2learn website:
https://programs.test2learn.org/course/view.php?id=88
You should log in or register here only after you review the educational content for this course.
To complete the course evaluation to receive your credits and certificate:
- Choose Register/Complete Course to complete the module.
- First time Users: If you have never completed training on this website, please select register in the upper right hand corner of the webpage.
- Returning Users: If you have completed training on this website, please log in in the upper right hand corner of the webpage.