Anatomic Pathology Case of the Month 1086
The UPMC Department of Pathology offers FREE continuing medical education (CME). Certificates and transcripts can be obtained at no charge through the University of Pittsburgh. The CME modules cover a broad range of topics relevant to pathologists and are presented as case reviews and lectures. While completing your CME requirements, consider the expertise of our faculty in helping you solve difficult clinical problems.
Topic for this Session: Review knowledge gaps with regard to neuropathologic neoplasms.
Physicians and other health care professionals.
Upon completion of this activity, participants should be able to:
- Increase their awareness of rare neuropathologic entities.
Suggested Additional Reading:
- Di Russo P, Perrini P, Pasqualetti F, Meola A, Vannozzi R. Management and outcome of high-grade multicentric gliomas: a contemporary single-institution series and review of the literature. Acta Neurochir (Wien). 2013 Dec;155(12):2245-51.
- Terakawa Y, Yordanova YN, Tate MC, Duffau H. Surgical management of multicentric diffuse low-grade gliomas: functional and oncological outcomes: clinical article. J Neurosurg. 2013 Jun;118(6):1169-75.
- Vaubel RA, Kollmeyer TM, Caron AA, et al. Synchronous gemistocytic astrocytoma IDH-mutant and oligodendroglioma IDH-mutant and 1p/19q-codeleted in a patient with CCDC26 polymorphism. Acta Neuropathol. 2017 Aug;134(2):317-319.
- Oktay Y, Ülgen E, Can Ö, et al. IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. Sci Rep. 2016 Jun 10;6:27569.
- González-Castro TB, Juárez-Rojop IE, López-Narváez ML, et al. Genetic Polymorphisms of CCDC26 rs891835, rs6470745, and rs55705857 in Glioma Risk: A Systematic Review and Meta-analysis. Biochem Genet. 2019 Aug;57(4):583-605.
- Huse JT, Diamond EL, Wang L, Rosenblum MK. Mixed glioma with molecular features of composite oligodendroglioma and astrocytoma: a true "oligoastrocytoma"? Acta Neuropathol. 2015 Jan;129(1):151-3.
- Wilcox P, Li CC, Lee M, Shivalingam B, et al. Oligoastrocytomas: throwing the baby out with the bathwater? Acta Neuropathol. 2015 Jan;129(1):147-9.
Course Director and Planning Committee:
Karen E Schoedel, MD - Professor of Pathology, Member of the Division of Anatomic Pathology, University of Pittsburgh
Wen Zhong, M.D - Neuropathology Fellow, Division of Neuropathology, University of Pittsburgh
Thomas Pearce, MD, PhD - Assistant Professor of Pathology, Department of Pathology, University of Pittsburgh
Conflict of Interest Disclosure:
No planners, members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.
In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
The University of Pittsburgh School designates this live activity for a maximum of 0.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Other Healthcare Professionals
Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.
The information presented at this activity represents the views and opinions of the individual presenters, and does not constitute the opinion or endorsement of, or promotion by, the UPMC Center for Continuing Education in the Health Sciences, UPMC / University of Pittsburgh Medical Center or Affiliates and University of Pittsburgh School of Medicine. Reasonable efforts have been taken intending for educational subject matter to be presented in a balanced, unbiased fashion and in compliance with regulatory requirements. However, each program attendee must always use his/her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.
- 0.50 AMA PRA Category 1 Credit™The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
- 0.50 Attendance
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