9th Annual Acute Kidney Injury Symposium
This symposium will promote the clinical knowledge related to diagnosis and personalized treatment of acute kidney injury (AKI). It will help to improve the care of critically ill patients who develop or are at risk for AKI. It will also promote communication and collaboration among experts and specialists treating and researching acute kidney injury. The understanding of AKI and the effective strategies for developing, implementing, and performing protocols for managing the condition will be enhanced. The symposium also serves as a platform to spread kidney awareness and to educate and share resources with patients and the community.
The symposium is targeted for doctors, fellows, researchers, and professionals in the medical and research fields of critical care medicine, transplantation, nephrology, and the renal-electrolyte division.
8:50-9:00 Welcome Drs. Bates, Kellum, Kleyman, Lakkis
Session I Scientific Presentations
9:00 – 9:15 Clinical Responses to Fatty Acid Nitroalkenes – Electrophilic Cysteine Bruce Freeman Proteome Modulators Currently in Phase 2 Trials for FSGS, PAH and Asthma
9:15 – 9:30 Enhancing Acute Kidney Injury Regeneration by Promoting Cellular Neil Hukriede Dedifferentiation
9:30 – 9:45 Early Warning Biomarkers for Acute Kidney Injury: Drug Sandra Kane-Gill Management Considerations
9:45 – 10:00 The Kidney Precision Medicine Project Paul Palevsky
10:00 – 10:15 Role of the Molecular Chaperone, GRP170, in Salt-Water Teresa Buck Homeostasis and AKI
10:15 – 10:25 Discussion/Moderator Thomas Kleyman
10:25 – 10:35 Break
Session 2 Abstract Presentations (No CME credit awarded)
10:35 – 10:40 Introduction Fadi Lakkis
10:40 – 10:50 #1
10:50 – 11:00 #2
11:00 – 11:10 #3 9th Annual Acute Kidney Injury Symposium Thursday, October 31, 2019 9:00am – 3:30pm Starzl Biomedical Science Tower Conference Room S120 200 Lothrop Street, Pittsburgh, PA 15261
11:10 – 11:20 #4
11:30 – 11:40 Voting/Group Picture
11:55 – Noon Abstract Awards
Session 3 Keynote Speakers
Introduction of Samir Parikh John Kellum
Noon-12:25 Metabolic Determinants of AKI Resistance—PGC1a-NAD+ Samir Parikh
12:25-12:35 Q & A
Introduction of Anupam Agarwal Thomas Kleyman
12:35-1:05 Heme Oxygenase-1 as a Protective Mechanism in AKI Anupam Agarwal
1:05-1:15 Q & A
Session 4 Scientific Presentations
1:30-1:45 Net Ultrafiltration and Outcomes in Critically Ill Raghavan Murugan
1:45-2:00 New Biomarkers for "Pre-AKI" and "Persistent AKI" John Kellum
2:00-2:15 Acute Kidney Injury Immediate Post Kidney Transplantation: Sundaram Hariharan What We Know, What We Don’t Know and Where Should We Go?
2:15-2:30 Activation of AMP-activated protein kinase (AMPK) during sepsis/inflammation improves survival by preserving Hernando Gomez cellular metabolic fitness
2:30-2:40 Discussion/Moderator Carl Bates
Session 5 Panel Presentation
2:50-3:30 Kidney Research Updates Drs. Bates, Kellum, Kleyman, Lakkis
- Anupam Agarwal, MD – University of Alabama at Birmingham School of Medicine; Executive Vice Dean, Director, Division of Nephrology; Birmingham, AL
- Carlton Bates, MD – University of Pittsburgh; Chief, Division of Nephrology; Children’s Hospital of Pittsburgh of UPMC; Pittsburgh, PA
- Teresa Buck, MD – University of Pittsburgh; Research Associate Professor; Department of Biological Sciences; Pittsburgh, PA
- Faye Cotton, BS – University of Pittsburgh; Project Coordinator; Pittsburgh, PA
- Michele Elder, RN, BSN - University of Pittsburgh; Operations Manager; Pittsburgh, PA
- Bruce Freeman, PhD – University of Pittsburgh; Irwin Fridovich Distinguished Professor and Chair; Department of Pharmacology and Chemical Biology; Pittsburgh, PA
- Hernando Gomez, MD – University of Pittsburgh; Assistant Professor, Department of Critical Care Medicine; Faculty for Center for Critical Care Nephrology; Pittsburgh, PA
- Sundaram Hariharan, MD – University of Pittsburgh; Professor of Medicine and Surgery; Medical Director of Kidney and Pancreas Transplantation; Thomas E Starzl Transplant Institute; Pittsburgh, PA
- Neil Hukriede, PhD – University of Pittsburgh; Professor and Vice-Chair Department of Developmental Biology; Pittsburgh, PA
- Sandra Kane-Gill, PharmD, MS, FCCM, FCCP – University of Pittsburgh; Associate Professor, Pharmacy and Therapeutics, School of Pharmacy; University of Pittsburgh Medical Center; Critical Care Medication Safety Officer, Department of Pharmacy; Pittsburgh, PA
- John Kellum, MD, MCCM – University of Pittsburgh; Director of the Center for Critical Care Nephrology; Department of Critical Care Medicine; Vice Chair for Research, CRISMA; Pittsburgh, PA
- Thomas Kleyman, MD – University of Pittsburgh; Chief, Renal-Electrolyte Division; Professor of Cell Biology, Professor of Pharmacology and Chemical Biology; Pittsburgh, PA
- Fadi Lakkis, MD – University of Pittsburgh; Frank and Athena Sarris Chair in Transplantation Biology; Professor of Surgery, Immunology, and Medicine; Scientific Director, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA
- Carmela Londino, MBA, MS – University of Pittsburgh; Program Administrator, Renal-Electrolyte Division; Department of Medicine; Pittsburgh, PA
- Raghavan Murugan, MD – University of Pittsburgh; Associate Professor of Critical Care Medicine and Clinical & Translational Science; Center for Critical Care Nephrology, CRISMA Center; Department of Critical Care Medicine; University of Pittsburgh Medical Center; Magee-Women’s Hospital, ICU Director & Chief of Critical Care Medicine; Director, Rapid Response Team; Pittsburgh, PA
- Amy Nye, BS – University of Pittsburgh, Thomas E. Starzl Transplantation Institute, Executive Administrator; Pittsburgh, PA
- Paul Palevsky, MD – University of Pittsburgh; Professor of Medicine; Renal-Electrolyte Division; Chief, Renal Section VA Pittsburgh Healthcare System; Pittsburgh, PA
- Samir Parikh, MD - Associate Professor of Medicine; Division of Nephrology; Director, Center for Vascular Biology Research; Associate Vice Chair for Research;Beth Israel Deaconess; Harvard Medical School; Boston, MA
All individuals in a position to control the content of this education activity including members of the planning committee, speakers, presenters, authors, and/or content reviewers have disclosed all relevant financial relationships with any entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by, patients.
The following relevant financial relationships were disclosed:
1. Anupam Agarwal – Grant/Research Support: Sanofi/Genzyme; Consultant: Akebia, Reata, Angion, Dynamed; Stockholder: Goldilocks Therapeutics
2. Bruce Freeman – Stockholder: Complexa, Brainstage, Inc., Creegh Pharma, Inc.; Scientific Advisor: Complexa, Brainstage; CEO and President: Creegh Pharma
3. John Kellum – Grant/Research Support: Astute Medical, bioMerieux, Baxter; Consultant: Astute Medical, bioMerieux, Baxter
4. Tom Kleyman – Consultant: Relypsa, Inc.
5. Raghavan Murugan – Grant/Research Support: NIH, La Jolla, AM Pharma, Bioporto
6. Paul Palevsky – Grant/Research Support: Dascena
7. Samir Parikh – Grant/Research Support: Baxter; Consultant: Aerpio, Alkermes, Cytokinetics, Janssen, Hope Pharma, Astellas, Mission Therapeutics; Other: Equity in Raksana; Inventor on patent filing from BIDMC related to NAD+
No other planners, members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.
In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME) and the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
The University of Pittsburgh School of Medicine designates this live activity for a maximum of 4.5 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Other health care professionals
Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.
- 4.50 AMA PRA Category 1 Credit™The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
- 4.50 Attendance
- Click on Register/Complete Course to attend the 9th Annual AKI Symposium. Everyone must use a CCE account to register for the course in order to attend, even if you’re not claiming education credits.
- If you don’t have an existing CCE account, click register on the gold band to create an account. Once you’ve successfully registered, click register again to RSVP for meals.
- If you already have an account with the UPMC Center for Continuing Education (CCE), click login on the gold band and enter your login information. Then, in the right hand corner search for aki symposium, and complete the registration and meal selection.