Overall, the goal of this activity is to enhance clinical knowledge of the baseline disease state as well as relevant guidelines and supporting literature to optimize pharmacotherapy for patients in DKA. Recent literature has provided new guidance into optimal fluid choices for patients with DKA, however the application of these recommendations is not widespread due to lack of knowledge and familiarity with the studies. Furthermore, the interdisciplinary team often requires guidance with electrolyte management, as patients in DKA may present with significant electrolyte derangements. It is absolutely critical that pharmacists understand the pathophysiology of DKA and the place in therapy of electrolyte replacement.