Neuroscience-Informed Precision Psychiatry
Basic neuroscientific research on the mechanisms underlying cognitive, affective, and social processes have been slow in penetrating real-world psychology/psychiatry clinics. This is a missed opportunity for maximizing and advancing our understanding of core patterns of psychopathology and treatment response in neuropsychiatric disorders. This series will bring together members from the neuroscience, medical, and psychiatry/psychology communities to translate basic science findings into real-world clinical practice.
This program was designed for physicians, nurses, nurse practitioners, psychologists, and social workers.
Upon completion of this activity, participants should be able to:
- Evaluate promising neuroscientific findings in the areas of emotion, socioemotional learning and development, cognition, and therapeutic change that have significant potential to improve prevention and intervention efforts for mental illness.
- Recognize common barriers to the translation and adoption of basic science in real-world clinical practice.
- Articulate the benefits of integrating neuroscientific research in clinical practice in terms of prevention, assessment, and treatment for neuropsychiatric disorders.
Suggested Additional Reading
- Williams LM (2016). Precision Psychiatry: A neural circuit taxonomy for depression and anxiety. The Lancet Psychiatry 3(5),472-480. PMID: 27150382 PMCID: PMC4922884 doi: 10.1016/S2215-0366(15)00579-9
- Williams LM (2017). Defining biotypes for depression and anxiety based on large-scale circuit dysfunction: A theoretical review of the evidence and future directions for clinical translation. Depression and Anxiety, 34(1): 9-24. (doi: 10.1002/da.22556). PMID: 27653321
- Goldstein-Piekarski AN, Staveland B, Ball T, Yesavage J, Korgaonkar MS, Williams LM (2018). Intrinsic functional connectivity predicts remission on antidepressants: A randomized-controlled trial to identify clinically applicable imaging biomarkers. Translational Psychiatry, 8(57). (doi: 10.1038/s41398-018-0100-3).
Leanne Williams, PhD - Professor & Associate Chair for Research Strategy and Oversight, Stanford University School of Medicine, Department of Psychiatry and Behavioral Sciences; Director, Education & Precision Medicine, VA Palo Alto Sierra-Pacific MIRECC
Leanne Williams, Ph.D., is a Professor of Psychiatry and Behavioral Sciences at Stanford University School of Medicine. She is the founding director of the Stanford Center for Precision Mental Health and Wellness and of the Stanford PanLab for Precision Psychiatry and Translational Neuroscience, Associate Chair of Translational Neuroscience in the Department of Psychiatry and Behavioral Sciences, and Director of Education and Precision Medicine at the Palo Alto VA Mental Illness Research, Education and Clinical Center.
Prior to joining the Stanford community, Dr. Williams was the founding chair of Cognitive Neuropsychiatry and directed the Brain Dynamics Center at Sydney Medical School. Her PhD was completed with a British Council Scholarship for study at Oxford University.
Dr. Williams' Center and translational programs integrate advanced neuroimaging, technology and digital innovation to transform the way we detect mental disorders, tailor interventions and promote wellness. She has developed the first taxonomy for depression and anxiety that quantifies brain circuits for diagnostic precision and prediction. Dr. Williams' research programs are supported by funding from the National Institutes of Health, spanning priority Research Domain Criteria, Human Connectome and Science of Behavior Change initiatives. She has contributed over 320 scientific papers to the field.
Judy Callan, PhD RN
Rudi De Raedt, PhD
Angela Fang, PhD
Ryan Jane Jacoby, Ph.D.
Maria Kryza-Lacombe, PhD
Andrew Peckham, PhD
Greg Siegle, PhD
Michael Thase, MD
Conflict of Interest Disclosure:
Dr. Jacoby receives grant/research support from the National Institute of Mental Health under award number K23 MH120351. She also receives salary and research support from the International OCD Foundation, the Charles A. King Trust Postdoctoral Research Fellowship Program (Bank of America, N.A., Co-Trustees), the Harvard University Mind Brain Behavior Initiative, the Harvard University Department of Psychiatry Livingston Fellowship Award, and the Harvard University Pershing Square Fund for Research on the Foundations of Human Behavior.
No other planners, members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.
The information presented at this CME program represents the views and opinions of the individual presenters, and does not constitute the opinion or endorsement of, or promotion by, the UPMC Center for Continuing Education in the Health Sciences, UPMC / University of Pittsburgh Medical Center or Affiliates and University of Pittsburgh School of Medicine. Reasonable efforts have been taken intending for educational subject matter to be presented in a balanced, unbiased fashion and in compliance with regulatory requirements. However, each program attendee must always use his/her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.
In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.
The maximum number of hours awarded for this Continuing Nursing Education activity is 1.0 contact hours.
Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.
All presenters disclosure of relevant financial relationships with any entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by, patients is listed above. No other planners, members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.
- 1.00 AMA PRA Category 1 Credit™The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
- 1.00 ANCCUPMC Provider Unit is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation
- 1.00 Attendance