Pulse: Out of Breath, Out of Options? Managing Steroid-Refractory Immune Checkpoint Inhibitor- induced Pneumonitis

November 20, 2025

While rare, steroid-refractory immune checkpoint inhibitor-induced pneumonitis carries a high mortality risk. A few second-line treatment options are available, but data regarding choice of therapy and efficacy is lacking. This presentation aims to highlight current literature surrounding second-line treatment options for steroid-refractory pneumonitis, focusing on comparing efficacy of IVIG and infliximab.

Target Audience

Pharmacist

Learning Objectives

1. Define the causes of pneumonitis, focusing on the oncologic agents associated with drug-induced pneumonitis.
2. Discuss the different treatment options that are available for steroid-refractory immune checkpoint inhibitor-induced pneumonitis.
3. Explain the current approach to treatment based on available literature comparing IVIG and infliximab.

Additional Information

AttachmentSize
PDF icon Disclosure + Objective Slides_Jamison.pdf314.78 KB
Course summary
Available credit: 
  • 1.00 ACPE Pharmacy
    The UPMC Center for Continuing Education in the Health Sciences is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a Provider of continuing pharmacy education.
Course opens: 
11/20/2025
Course expires: 
12/20/2025
Event starts: 
11/20/2025 - 12:00pm EST
Event ends: 
11/20/2025 - 1:00pm EST
Add to calendar: 

While rare, steroid-refractory immune checkpoint inhibitor-induced pneumonitis carries a high mortality risk. A few second-line treatment options are available, but data regarding choice of therapy and efficacy is lacking. This presentation aims to highlight current literature surrounding second-line treatment options for steroid-refractory pneumonitis, focusing on comparing efficacy of IVIG and infliximab.

UPMC Presbyterian/ Mercy
Pittsburgh, PA
United States

Hanna Jamison, PharmD

 

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

 

Pharmacy (CPE)

This knowledge-based activity provides 1.0 contact hours of continuing pharmacy education credit.

 

Available Credit

  • 1.00 ACPE Pharmacy
    The UPMC Center for Continuing Education in the Health Sciences is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a Provider of continuing pharmacy education.
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