Pulse: Farewell to the Swell: Management of ACE inhibitor-induced angioedema

March 6, 2025

ACE inhibitor-induced angioedema accounts for approximately 30% of all angioedema cases, but no medications currently have FDA approval for this indication. Medications commonly used for histamine-mediated angioedema are not effective, and other medications with potential benefit are expensive with limited high-quality evidence. This presentation will increase pharmacists’ knowledge of medications used for ACE inhibitor-induced angioedema and their benefits in this life threatening event.

Target Audience

Pharmacist

Learning Objectives

1. Describe the mechanism by which ACE inhibitors induce angioedema.

2. Identify angioedema therapies with proven benefit for improving airway management and reducing symptom duration.

3. Recognize medications with increased risk of drug-induced angioedema following an ACE inhibitor-induced event.

Additional Information

Course summary
Available credit: 
  • 1.00 ACPE Pharmacy
    The UPMC Center for Continuing Education in the Health Sciences is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a Provider of continuing pharmacy education.
Course opens: 
03/06/2025
Course expires: 
04/06/2025
Event starts: 
03/06/2025 - 12:00pm EST
Event ends: 
03/06/2025 - 1:00pm EST

ACE inhibitor-induced angioedema accounts for approximately 30% of all angioedema cases, but no medications currently have FDA approval for this indication. Medications commonly used for histamine-mediated angioedema are not effective, and other medications with potential benefit are expensive with limited high-quality evidence. This presentation will increase pharmacists’ knowledge of medications used for ACE inhibitor-induced angioedema and their benefits in this life threatening event.

UPMC Presbyterian/ Mercy
Pittsburgh, PA
United States

Michael Hair, PharmD

 

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

 

Pharmacy (CPE)

This knowledge-based activity provides 1.0 contact hours of continuing pharmacy education credit.

 

Available Credit

  • 1.00 ACPE Pharmacy
    The UPMC Center for Continuing Education in the Health Sciences is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a Provider of continuing pharmacy education.
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