Pulse: Not Just for Neurology: The Use of Hypertonic Saline for Diuretic Resistance
New medications and new guidelines are constantly being released. Pharmacists need a mechanism to keep up with these new medications and guidelines.
Diuretic resistance is a problem faced within the heart failure population that has limited options for management. The use of concomitant hypertonic saline with a loop diuretic has been proposed as a possible treatment option. This presentation seeks to discuss the risks vs benefits and ideal patient population for utilization of adjunctive hypertonic saline for refractory diuresis
Target Audience
Pharmacist
Learning Objectives
1. Define the criteria needed for diagnosis of diuretic resistance.
2. Describe the pathophysiology of diuretic resistance and current management options including sequential nephron blockade.
3. Discuss current literature that assesses the efficacy and safety of hypertonic saline in diuretic resistance.
Additional Information
Attachment | Size |
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Audience Disclosure slide_25.pptx | 460.2 KB |
Yaeger PULSE 2 Handout .pdf | 333.41 KB |
New medications and new guidelines are constantly being released. Pharmacists need a mechanism to keep up with these new medications and guidelines.
Diuretic resistance is a problem faced within the heart failure population that has limited options for management. The use of concomitant hypertonic saline with a loop diuretic has been proposed as a possible treatment option. This presentation seeks to discuss the risks vs benefits and ideal patient population for utilization of adjunctive hypertonic saline for refractory diuresis
Kayleigh Yaeger, PharmD
In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Pharmacy (CPE)
This knowledge-based activity provides 1.0 contact hours of continuing pharmacy education credit.
Available Credit
- 1.00 ACPE PharmacyThe UPMC Center for Continuing Education in the Health Sciences is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a Provider of continuing pharmacy education.