Psychosocial Determinants of Sleep & Physical Health Symposium:
 

Osea Giuntilla, PhD:
• Economic frameworks for understanding of sleep behavior
• Effects of sleep deprivation on human capital, health and economic performance
• Factors influencing sleep choice, examining the factors affecting the allocation of time to sleep and behavioral mechanisms that may explain suboptimal sleep choices.

Rebecca Thurston, PhD:
• Factors affecting sleep and vasomotor menopausal symptoms in midlife women
• Greater sleep disruption in midlife women is associated with poorer cardiovascular outcomes

Sanjay Patel, MD, MS:
• Racial differences in sleep
• Differentiate racial differences from disparities in sleep health
• Explain how structural racism impacts sleep health

David J. Kupfer Keynote Lecture: Tired and Stressed: The impact of sleep and circadian regulation on oxidative stress and lifespan
 

Mimi Shirasu-Hiza, PhD:
• Oxidative stress is associated with many human diseases, including cardiac disease, metabolic dysfunction, and neurodegenerative diseases
• Many of those diseases are also associated with defects in sleep or circadian regulation
• We hypothesize that one function of sleep and circadian regulation is to defend the brain and body against oxidative stress
• Using Drosophila, we will show one example of each: sleep is required for defense against oxidative stress and circadian regulated metabolism is required to modulate basal oxidative stress and regulate aging

Sleep & Mental Health Symposium:
 

Zach Freyberg, MD:
• Pancreatic dopamine is a powerful modulator of insulin release in pancreatic beta cells.
• Many components of the pancreatic beta cell dopaminergic machinery are under circadian control.
• Antipsychotic drugs may produce their metabolic side effects in part via their disruption of circadian expression of the beta cell dopamine machinery

Yanhua Huang, PhD
• Understand the necessity of using animal models.
• Understand that changes in sleep may lead to changes in reward seeking behaviors.
• Identify a top-down control mechanism that is compromised by loss of sleep, and its impact on reward-elicited behaviors, including substance use.

Peter Franzen, PhD:
• Understand the changes in developmental sleep-wake patterns during adolescence, and their links to mental health.
• Review experimental evidence that sleep loss alters neural systems underlying reward and emotion regulation.
• Review new evidence linking sleep to suicidality among ultra-high risk youth