Optical Genome Mapping 10.30.24

Target Audience

Physicians

Learning Objectives

Describe the rationale for advancing cytogenomics testing to capture the broad range of chromosomal structural variants. He will explain the framework involved in carrying out wet lab validation of optical genome mapping in a clinical cytogenetics setting. He will also illustrate through case examples, optical genome mapping data analysis and steps involved in prioritizing high confidence chromosomal structural variants. Optical Genome mapping will help study chromosomal structural variations (SVs). Pan-Caner Analysis of Whole Genomes Consortium: The total count of SVs discovered per genome has increased from 5k in the 1000 genomes project to more than 27k in 2021 multi-platform from sequencing and mapping efforts. The main purpose of Dr. Aarabi's presentation is to explain what Optical Genome Mapping is. Our laboratory will start processing samples using the new OGM machine. Optical Genome mapping is an approach to analyze large genomes and their structural features at a high resolution. It uses linearized strands of ultra high molecular weight DNA that are longer than the DNA analyzed in current second-generation sequencing methods

Course summary
Available credit: 
  • 1.00 AMA PRA Category 1 Credit™
    The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
  • 1.00 Attendance
Course opens: 
10/29/2024
Course expires: 
03/28/2025

Disclaimer Statement

The information presented at this CME program represents the views and opinions of the individual presenters, and does not constitute the opinion or endorsement of, or promotion by, the UPMC Center for Continuing Education in the Health Sciences, UPMC / University of Pittsburgh Medical Center or Affiliates and University of Pittsburgh School of Medicine.  Reasonable efforts have been taken intending for educational subject matter to be presented in a balanced, unbiased fashion and in compliance with regulatory requirements. However, each program attendee must always use his/her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.

Magee Womens Hospital
Conference Room 2131 Pittsburgh, PA
Pittsburgh, PA
United States

Dr. Mahmoud Aarabi, MD, PhD, FACMG, Medical Director, UPMC Cytogenetics Laboratories

Disclosure Statement: No members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships with any proprietary entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by, patients to disclose.

 

Accreditation and credit designation

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician (CME)

The University of Pittsburgh School designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Other Healthcare Professionals

Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.

Available Credit

  • 1.00 AMA PRA Category 1 Credit™
    The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
  • 1.00 Attendance
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