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ForwardPulse - Out with the old and in with the new: Should levetiracetam replace phenytoin as the agent of choice for seizure prophylaxis following traumatic brain injury?
New medications and new guidelines are constantly being released. Pharmacists need a mechanism to keep up with these new medications and guidelines.
The Brain Trauma Foundation's Guidelines for Severe Traumatic Brain Injury recommend prophylaxis with phenytoin after traumatic brain injury for the first seven days post-injury to prevent early post-traumatic seizures. There is growing evidence that levetiracetam may be an optimal agent for seizure prophylaxis in this population.
Target Audience
Pharmacist
Learning Objectives
1. Describe the pathophysiology and implications of seizures following a traumatic brain injury.
2. Discuss the current standard of practice and guideline recommendations for seizure prophylaxis in patients with traumatic brain injury.
3. Identify the pros and cons of phenytoin vs levetiracetam for post-traumatic seizure prophylaxis.
Additional Information
| Attachment | Size |
|---|---|
 Audience Disclosure slide_3.pptx | 459.41 KB |
 Collier_PULSE handout.docx | 32.32 KB |
| Pulse 10-26-22.docx | 17.51 KB |
New medications and new guidelines are constantly being released. Pharmacists need a mechanism to keep up with these new medications and guidelines.
The Brain Trauma Foundation's Guidelines for Severe Traumatic Brain Injury recommend prophylaxis with phenytoin after traumatic brain injury for the first seven days post-injury to prevent early post-traumatic seizures. There is growing evidence that levetiracetam may be an optimal agent for seizure prophylaxis in this population.
Victoria Collier, PharmD
In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Pharmacy (CPE)
This knowledge-based activity provides 1.0 contact hours of continuing pharmacy education credit.
Available Credit
- 1.00 ACPE PharmacyThe UPMC Center for Continuing Education in the Health Sciences is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a Provider of continuing pharmacy education.